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95% Bodybuilding Peptide Powder Igf-1 Lr3,Human Growth Peptides Igf-1 Lr3

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95% Bodybuilding Peptide Powder Igf-1 Lr3,Human Growth Peptides Igf-1 Lr3

China 95% Bodybuilding Peptide Powder Igf-1 Lr3,Human Growth Peptides Igf-1 Lr3 supplier
95% Bodybuilding Peptide Powder Igf-1 Lr3,Human Growth Peptides Igf-1 Lr3 supplier 95% Bodybuilding Peptide Powder Igf-1 Lr3,Human Growth Peptides Igf-1 Lr3 supplier

Large Image :  95% Bodybuilding Peptide Powder Igf-1 Lr3,Human Growth Peptides Igf-1 Lr3

Product Details:

Place of Origin: Wuhan,Hubei
Brand Name: Yuancheng
Certification: ISO9001
Model Number: 946870-92-4

Payment & Shipping Terms:

Minimum Order Quantity: 10 vials
Price: Negotiate
Packaging Details: 10g,100g,500g,1kg ect.
Delivery Time: About 4-7 working days
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin
Supply Ability: 5KG/Month
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Detailed Product Description
Name: Igf-1 Lr3 Purity: 95%
Appearance: Lyophilized Powder CAS: 946870-92-4
Packing: 1mg/vial MOQ: 10 Vial

95% Bodybuilding Peptide Powder Igf-1 Lr3,Human Growth Peptides Igf-1 Lr3

Name:IGF-1 LR3
Appearance:lyophilized powder
Assay:95%
Packing:1mg/vial

IGF-1 LR3, also known as Long Arg3 IGF-1, is a recombinant protein analogue of human Insulin-Like Growth Factor-1 that has a molar mass of 9,200 Daltons and is comprised of 83 amino acids. IGF-1 LR3 comprises the complete IGF-1 sequence, but with a 13 amino acid extension on the B-Terminus domain and the substitution of an Arginine for the Glutamic Acid at position 3. The LR3 analogue of IGF-1 was created with the intent to drastically increase the biological activity of the protein and IGF-LR3 is several times more potent than rhIGF-1. This specific sequence alteration has decreased the affinity of binding to the IGFBPs, which control the biological actions of IGF-1 and prevent the protein from reaching the IGF-1 receptors.

IGF-1 LR3 is an 83 amino acid analogue of human IGF-1 that has been modified to include a 13 amino acid extension on its N-Terminus and the substitution of an Arginine amino acid for Glutamine at position 3. While IGF-1 LR3 is comprised of the the complete human IGF-1 sequence, these modifications have rendered the LR3 version to be much more potent than IGF-1 in-vitro and in-vivo. The result of these modifications is that IGF-1 LR3 does not bind as strongly to the IGFBPs, which modify the biological actions of IGF-1. Resultantly, IGF-1 LR3 binds to the type 1 IGF-1 receptor with similar affinity to that of wild type IGF-1, but with higher biological activity and has several advantages over recombinant insulin. The supplementation of mammalian cell cultures with Long R3 IGF-1 at a much lower concentration results in more highly elevated productivity than with standard concentrations of insulin and/or standard IGF-1. IGF-1 LR3 is better able to stimulate the type 1 IGF receptor and thus induce a higher level of activation of intracellular signaling, which is responsible for promoting cell proliferation and the inhibition of apoptosis.

IGFB Binding and Increased Biological Activity:
By resisting IGFBP-binding, IGF-1 LR3 has a greater physiologic effect than IGF-1 does. The longer duration of action allows for smaller amounts to be used with the same effects. Some IGF-1 derivatives, such as the GPE derivative, made up of just the last three N-terminal amino acids of the IGF-1 protein, have been shown to have therapeutic effects in neurological injuries like stroke. Most studies concerning the effects of IGF-1 derivatives have been carried out in animal models, with little to no data available for humans.

Insulin Like Growth Factor Receptor Interactions:
IGF-1 Long R3 binds to at least two cell surface receptors: IGF-1R and the insulin receptor. The IGF-1 receptor is referred to as the "physiologic" receptor because IGF-1 binds to it with significantly higher affinity (approximately 100 times higher) than it does to the insulin receptor. By binding to IGF-1R, IGF-1 can affect metabolism, cell growth (hypertrophy), differentiation and cell division (hyperplasia), prevention of cell death (apoptosis), normal development, and even malignant growth. IGF-1R has been implicated in several different types of cancer include breast, prostate, and lung cancer. IGF-1 also binds to the insulin receptor and activates it, thereby encouraging cells to take up glucose from the blood stream. The effects of IGF-1 on muscle cells are three-fold. Firstly, IGF-1 encourages hyperplasia, or an increase in the number of muscle cells. Secondly, IGF-1 has a strong effect on skeletal muscle - In regards to the life span of satellite cells. Satellite cells support muscle cells, providing them with needed nutrients and helping them to operate efficiently. By increasing the lifespan of these cells, IGF-1 helps to increase their number with muscle tissue. Finally, IGF-1 encourages differentiation of myoblasts, which is to say that it encourages the conversion of stem cell progeny from nonspecific pluripotent stem cells into dedicated muscle tissue. In this way, IGF-1 increases the rate of muscle development by increasing the rate at which generic stem cells are converted to muscle cells.

 

The peptides list:

 

Name Quantity/vial
MGF 2mg
MGF 5mg
PEG MGF 2mg
CJC-1295 with DAC 2mg
CJC-1295 without DAC 2mg
PT-141 10mg
MT-2 10mg
GHRP-2 5mg
GHRP-2 10mg
GHRP-6 5mg
GHRP-6 10mg
Ipamorelin 2mg
Hexarelin 2mg
Sermorelin 2mg
Oxytocin 2mg
TB500 2mg
Pentadecapeptide BPC 157 2mg
HGH 176-191 2mg
Triptorelin 2mg
Tesamorelin 2mg
Gonadorelin 2mg
Gonadorelin 10mg
DSIP 2mg
Selank 5mg
Epitalon 10mg
Follistatin 344 1mg
Follistatin 315 1mg
ACE-031 1mg
GDF-8 1mg
IGF-1 LR3 1mg

 

 

Our advantages:
1) Best prices with satisfied quality.
2) Rich experienced in delivering the parcels to you.
3) Enough stock ensure the prompt delivery time.
4) Good after-sales service.
5) Package will be reshipped if sent failed.
6) Specials are possible when the order is big enough.
7)For most products we can provide you a free sample, while the shipping cost should undertake by your

side.

 

95% Bodybuilding Peptide Powder Igf-1 Lr3,Human Growth Peptides Igf-1 Lr3

 

 

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Contact Person: Nancy

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