Hangzhou Fuluo Biological Technology Co.,Ltd.

  High quality, competitive price, fast delivery

         WhatsApp:+8615372437208  

         E-mail:nancypeng@ycphar.com

Home
Products
About Us
Factory Tour
Quality Control
Contact Us
Request A Quote
Home ProductsWeight Loss Powder

98.9% Weight Loss Powder Pharmaceutical Raw Materials Methyl-synephrine

Good quality Testosterone Steroids for sales
Good quality Testosterone Steroids for sales
The Anavar suspended way better than it usual doed for me.Those could be postitive things.I'm Just making sure.

—— Jason

Your product help me put on nice clean gains no water retention or unwanted fat

—— Leo

Hey Nancy, Sorry for not replying,Ive been in the hospital for some time.I had some testers use both yohimbine and cialis which they said worked exce

—— Gordon

Thanks for understanding.i had to tell your competitors to go away.I only buy from you.in loyal.you've all been very good to me.I'll need 200g of test

—— Jordan

thanks for your continued great service. Jordy

—— Jordy

Hi Nancy! Just did HPLC test on RAD 140 now: Very happy here

—— Francois

I'm Online Chat Now

98.9% Weight Loss Powder Pharmaceutical Raw Materials Methyl-synephrine

China 98.9% Weight Loss Powder Pharmaceutical Raw Materials Methyl-synephrine supplier
98.9% Weight Loss Powder Pharmaceutical Raw Materials Methyl-synephrine supplier 98.9% Weight Loss Powder Pharmaceutical Raw Materials Methyl-synephrine supplier

Large Image :  98.9% Weight Loss Powder Pharmaceutical Raw Materials Methyl-synephrine

Product Details:

Place of Origin: Wuhan,Hubei
Brand Name: Yuancheng
Certification: ISO9001
Model Number: Methyl-synephrine

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiatable
Packaging Details: Discreet packaging
Delivery Time: 4-7 working days
Payment Terms: T/T, Western Union, MoneyGram, Bank Transfer
Supply Ability: 1000kg/Month
Contact Now
Detailed Product Description
Name: Methyl-synephrine CAS: 365-26-4、7437-54-9
MF: C10H15NO2 MW: 181.2316
Purity: 98.9% Appearance: Off-white Powder

98.9% Pharmaceutical Raw Materials Methyl-synephrine For Fat Loss

Methyl-synephrine
CAS:365-26-4,7437-54-9
MF:C10H15NO2
MW:181.2316
Purity:98.9%
Appearance:off-white powder

 

Synephrine is an adrenergic agonist that has gained popularity as being an ephedrine alternative. It's found in many species of plants, however the main source today for synephrine is citrus aurantium, aka "bitter orange". Once ephedra was banned, many supplement companies switched to synephrine or methyl-synephrine for their fat loss products.

 

Methyl-synephrine is often compared to octopamine and suggested to primarily activate beta-3 receptors. Some data suggests the increase in thermogenic activity caused by synephrine may not equate to clinically significant weight loss over time, however methyl-synephrine would likely have a more pronounced effect.

 

Physiological effects:
A study using a bitter orange extract standardized for 27 mg synephrine failed to induce any changes in hemodynamics. Conversely, in another study using twice the amount, significant effects were observed for heart rate, systolic pressure, and diastolic pressures, in which all values increased. This would indicate that the minimum threshold dose to elicit adrenergic activity to be somewhere between 27 mg and 54 mg for adult males.

 

Although synephrine has demonstrated an ability to induce lipolysis (fat burning) by activating beta-3 receptors en vitro, its efficiency in doing so en vivo is greatly limited because of its inherent affinity for alpha receptors. The dose required to sufficiently trigger lipolysis within adipocytes would be intolerable due to its effects on hemodynamics.

 

The primary difference between synephrine and methylsynephrine is the addition of a methyl group on the alpha carbon. This has extensive pharmacodynamic implications as it increases the affinity of the compound for beta-receptors.

 

Methylsynephrine has been used clinically for orthostatic hypotension due to its effects on stroke volume, ejection fraction, and cardiac index. It has been used in doses of up to 120mg in healthy adults with no adverse effects. Even at this dose, diastolic pressure decreased, which is evidence for very little alpha-adrenergic activity.

 

Furthermore, it had no effect on heart rate or mean arterial pressure. Some of methylsynephrines therapeutic efficacy is mediated by acting as a norepinephrine-releasing agent, and also by inhibiting its uptake. The majority of methylsynephrines pharmacological appeal resides in its ability to activate beta receptors, which is exemplified through its effects on the heart and haemodynamics. This also implies significant beta-3 activity and an ability to induce lipolysis which is consistent with some of its marketing claims.

 

Another deviation from synephrine is methylsynephrines limited propensity to activate alpha-2 receptors on platelets. This would avoid the complications of intravascular clotting, which has resulted in myocardial infarction mortality associated with synephrine, although allow for the possibility of cerebral hemorrhage.

 

The COA of Methyl-synephrine:

 

Product name

 

 

Methyl-synephrine

CAS No.

 

365-26-4,7437-54-9

Outer Packing

 

1kg

 

Production date

 

2016.12.15

Shelf life

 

2 years

Standard adopted

 

Enterprise Standard

 

Items of analysis Specification Results

 

Appearance

 

Visual

 

White powder

 

 

Complies

 

 

Loss on drying

 

USP<731>

 

1.0% max

 

 

0.1%

 

 

Heavy metals

 

USP<231>method III

 

10.0ppm max

 

 

Complies

 

 

Assay

 

HPLC

 

98.0% min

 

 

98.9%

 

 

Appearance

 

Visual

 

White powder

 

 

Complies

 

 

Loss on drying

 

USP<731>

 

1.0% max

 

 

0.1%

 

 

Heavy metals

 

USP<231>method III

 

10.0ppm max

 

 

Complies

 

 

Assay

 

HPLC

 

98.0% min

 

 

98.9%

 

Conclusion Qualified

 

 

Contact Details
Hangzhou Fuluo Biological Technology Co.,Ltd.

Contact Person: Nancy

Send your inquiry directly to us (0 / 3000)