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|Purity:||99.5%||Appearance:||White Crystalline Powder|
|Molecular Formula:||C18H19NOS.HCl||Molecular Weight:||333.88|
99.5% Antidepressant Raw Powder Duloxetine HCL
Appearance:white crystalline powder
Duloxetine Hydrochloride is the hydrochloride salt of duloxetine, a fluoxetine derivative belonging to the class of selective serotonin (5-HT) and norepinephrine (NE) reuptake inhibitors (SSNRIs) and exhibiting antidepressant activity. Duloxetine selectively prevents the reuptake of 5-HT and NE via transporter complexes on the pre-synaptic membrane, thereby increasing the level of these neurotransmitters within the synaptic cleft. As a result, this agent potentiates serotonergic and noradrenergic activities in the central nervous system, and alleviates depression and neuropathy sensations, such as pain and tingling. Furthermore, duloxetine does not show significant affinity for dopaminergic, adrenergic, cholinergic, histaminergic, opioid, glutamate, and gamma-aminobutyric acid (GABA) receptors.
Duloxetine HCL is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).
Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.
The COA of Duloxetine HCL:
|Product name||Duloxetine HCL|
|CAS No.||136434-34-9||Outer Packing||1KG foil bag|
|Production date||2017.10.10||Shelf life||2019.04.09|
|Standard adopted||Enterprise Standard|
|Items of analysis||Specification||Results|
|Description||White or off- white crystalline powder||White crystalline powder|
|Loss on drying (%)||Not more than 0.5%||0.20%|
|Assay by HPLC(A%)||Not less than 98.0%||99.50%|