Hangzhou Fuluo Biological Technology Co.,Ltd.
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|Purity:||99.8%||Appearance:||White Crystalline Powder|
|Molecular Formula:||C15H21F3N2O2 · C4H4O4||Molecular Weight:||434.41|
99.8% Fluvoxamine maleate white powder, USP Standard Fluvoxamine maleate
Appearance:white crystalline powder
Molecular formula:C15H21F3N2O2 · C4H4O4
Molecular weight: 434.41
Fluvoxamine maleate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) belonging to the chemical series, the 2-aminoethyl oxime ethers of aralkylketones.This class of drugs is used to treat depression, anxiety, and other mood disorders.
luvoxamine's only FDA approved indication is in the treatment of OCD, although in other countries (e.g. Australia,UKand Russian Federation) it also has indications for major depressive disorder. Fluvoxamine has been found to be useful in the treatment of major depressive disorder, anxiety disorders such as panic disorder, social anxiety disorder, and posttraumatic stress disorder, and other obsessive-compulsive spectrum disorders. Fluvoxamine is indicated for children and adolescents with OCD.The drug works long-term, and retains its therapeutic efficacy for at least a year.It has also been found to possess some analgesic properties in line with other SSRIs and tricyclic antidepressants.
Some evidence shows fluvoxamine may be a helpful adjunct in the treatment of schizophrenia, improving the depressive, negative, and cognitive symptoms of the disorder.Its actions at the sigma receptor may afford it a unique advantage among antidepressants in treating the cognitive symptoms of schizophrenia.
The COA of Fluvoxamine maleate:
|Product name||Fluvoxamine maleate|
|CAS No.||61718-82-9||Outer Packing||1kg|
|Production date||20160126||Shelf life||20181125|
|Standard adopted||Complies with the BP2014|
|Items of analysis||Specification||Results|
|Characterisics||A white to almost white crystalline powder||A white crystalline powder|
|Solubility||Sparingly soluble in water, freely soluble in Ethanol(96%) and in methanol||Sparingly soluble in water, freely soluble in Ethanol(96%) and in methanol|
|Identification||According to Standard||Complies|
|Acetonitrile||Not more than 100ppm||18ppm|
|Related substances (According to BP2014)Impurity B||Not more than 0.5%||0.01%|
|Impurity C||Not more than 0.3%||0.05%|
|Impurity A||Not more than 0.2%||0.00%|
|Impurity D||Not more than 0.15%||0.00%|
|Impurity F+G||Not more than 0.3%||0.02%|
|Any other secondary impuritie peak||Not more than 0.1%||0.03%|
|The total impurities||Not more than 1.0%||0.15%|
|Heavy metals||Maximum 20 ppm||< 20 ppm|
|Loss on drying||Not more than 0.5%||0.22%|
|Sulphated ash||Not more than 0.1%||0.03%|
|Assay||Not less than 99.0% and not more than 101.0% (Calculated with reference to the dried substance)||99.80%|