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|CAS Register Number:||120511-73-1||Molecular Formula:||C17H19N5|
|Molecular Weight:||293.37||Appearance:||White Powder|
Arimidex (anastrozol) is the aromatase inhibitor of choice. Arimidex's mechanism of action - blocking conversion of aromatizable steroids to estrogen - is in contrast to the mechanism of action of anti-estrogens such as clomiphene (Clomid) (Nolvadex), which block estrogen receptors in some tissues, and activate estrogen receptors in others.
Arimidex can be referred to as an aromatase inhibitor which helps prevent estrogen production in females. Research has shown that the estrogen hormone is responsible for the creation of breast cancer tumors in women. Arimidex is the drug administered to intercept the enzyme aromatase, which is a substance that assists the body tissues in producing estrogen. Arimidex is a popular drug in the battle against breast cancer. It is by and large, a hormonal treatment which can prevent the recurrence of breast cancer. Arimidex, also known as Anastrozole is not a steroid.
Arimidex is known to have diminished estrogen way too much in some patients. This is why blood tests or salivary tests are recommended after a week of usage to determine whether the dosage is appropriate.
Arimidex tends to work quite differently than the traditional anti-estrogens. Anti-estrogens like Clomid or Nolvadex tend to intercept estrogen receptors in certain tissues while activating them in others.
Meanwhile, Arimidex directly intercepts the enzyme aromatase. When a patient has been recommended the use of Arimidex, Clomid use along with is unnecessary. Doing so may have some benefits.
Arimidex is generally used for all stages and forms of breast cancer which are classified to be estrogen receptor positive. In case the patient has estrogen receptor negative or triple negative cancer, the usage of Arimidex is unlikely to help.
Anastrozol is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to
gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of
aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren.
It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably
salivary tests, should be taken after the first week of use to determine if the dosing is correct.
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