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|Chemical Name:||Pentadecapeptide BPC 157||CAS NO.:||137525-51-0|
High Quality 99% CAS 137525-51-0 Pentadecapeptide BPC 157 for Bodybuilding
Alias: Booly Protection Compound 15, Pentadecapeptide, BPC 157
Sequence: Gly-Glu-Pro-Pro-Pro-Gly- Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Appearance: White Lyophilized Powder
Place of Origin: China
Method of Analysis: HPLC
BPC 157 (Body Protection Compound-157) is a pentadecapeptide made up of 15 amino
acids. The amino acids sequence in BPC 157 is similar to a portion of the human BPC
amino acid sequence.
BPC 157 has a strong anti-inflammatory activity in both acute and chronic inflammation
models. In fact, preliminary results in clinical trials suggest that BPC 157 may become an
important therapeutic tool for the treatment of inflammatory bowel disease. BPC 157 was
shown to accelerate wound healing and to have a marked angiogenic effect. In addition, it
significantly facilitates the healing of bone fracture in rats. This peptide also exhibits an
osteogenic effect significantly improving the healing of segmental bone defect.
BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat
FITC-phalloidin staining was able to demonstrate that BPC 157 induces F-actin formation in
fibroblasts. Likewise, Western blot analysis was able to detect the production and activation
of paxillin and FAK proteins. The western blot analysis also showed that BPC 157 increases
the extent of phosphorylation of paxillin and FAK proteins without affecting the amounts
The Usage of BPC 157:
BPC 157 has been shown in studies to heal torn quadriceps muscles, detached achilles
tendon, muscles that have been damaged/crushed. Demonstrating dramatic fast recovery
from muscle tears. Tendon to bone healing - increased ligament healing, BPC 157 has a
variety of protective effects in the organs.
Clinical trials demonstrate healing and prevention of stomach ulcers and it is being studied as
a burn treatment. Trials show it may help repair some liver damage after prolonged chronic
alcohol exposure. No adverse reactions have been seen in clinical trials.
BPC 157 peptide has been shown to heal a variety of wounds in all areas researched,
including internal organs, muscles, ligaments, tendons, skin, internal lacerations from
it can have a use in the medical industry help heal and get rid of stomach ulcers caused by
people abusing NSAID drugs
200mcg being a medium dose up to 500mcg … depending on severity of issue ( if severe)
dose 2x a day at 350 mcg totaling 700 mcg.
The storage of BPC157:
Just like another peptide keep it away from UV/sunlight. it can stay in room temp for up to
10 weeks, however for best storage/results store in a fridge and use until vial is run out then
discard of it. For other BPC 157, they can stay in the fridge too as they;ll last up to 6
months, whereas if you had more you can store in the freezer( up to 2 years).
|CJC-1295 with DAC||2mg|
|CJC-1295 without DAC||2mg|
|Pentadecapeptide BPC 157||2mg|
|Product Name||Pentadecapeptide BPC 157|
|Alias||Booly Protection Compound 15|
|Appearance||White Lyophilized Powder|
Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including transected rat Achilles tendon. This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 157 significantly accelerated the outgrowth of tendon explants. Cell proliferation of cultured tendon fibroblasts derived from rat Achilles tendon was not directly affected by BPC 157 as evaluated by MTT assay. However, the survival of BPC 157-treated cells was significantly increased under the H(2)O(2) stress. BPC 157 markedly increased the in vitro migration of tendon fibroblasts in a dose-dependent manner as revealed by transwell filter migration assay. BPC 157 also dose dependently accelerated the spreading of tendon fibroblasts on culture dishes. The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts. The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose dependently increased by BPC 157 while the total amounts of protein was unaltered. In conclusion, BPC 157 promotes the ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts, which is likely mediated by the activation of the FAK-paxillin pathway.
BPC 157 has a strong anti-inflammatory activity in both acute and chronic inflammation models. In fact, preliminary results in clinical trials suggest that BPC 157 may become an important therapeutic tool for the treatment of inflammatory bowel disease. BPC 157 was shown to accelerate wound healing and to have a marked angiogenic effect. In addition, it significantly facilitates the healing of bone fracture in rats. This peptide also exhibits an osteogenic effect significantly improving the healing of segmental bone defect. BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat quadriceps muscle.
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