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Local Anesthetic Agents Pain Killer Tetracaine / Tetracaine HCl CAS 136-47-0

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Local Anesthetic Agents Pain Killer Tetracaine / Tetracaine HCl CAS 136-47-0

China Local Anesthetic Agents Pain Killer Tetracaine / Tetracaine HCl CAS 136-47-0 supplier
Local Anesthetic Agents Pain Killer Tetracaine / Tetracaine HCl CAS 136-47-0 supplier Local Anesthetic Agents Pain Killer Tetracaine / Tetracaine HCl CAS 136-47-0 supplier

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Product Details:

Place of Origin: Wuhan,Hubei
Brand Name: Yuancheng
Certification: ISO9001
Model Number: 136-47-0

Payment & Shipping Terms:

Minimum Order Quantity: 100G
Price: Negotiate
Packaging Details: Discreet packaging
Delivery Time: About 4-7 working days
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin
Supply Ability: 5000KG/Month
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Detailed Product Description
Molecular Formula: C15H25ClN2O2 Molecular Weight: 300.82
CAS: 136-47-0 Assay: 97-101%
Standard: Enterprise Standard Delivery: Express Courier.

Quick detail :

Product Name Tetracaine
Synonym Anetain, Amethocaine, Pontocaine,Ametop,Dicaine
CAS 94-24-6
MF C15H24N2O2
MW 264.36
EINECS 202-316-6
Assay 99%
Quality Standards Enterprise Standard/Pharma Grade
Appearance White powder
Package 25kg/Drum

What is the Tetracaine ?

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Specification :

Test Items Specification Test Results
Appearance Fine, white, crystalline, odorless powder confirm
Identification ABC in Pass confirm
Solubility Very soluble in water, soluble in Alcohol;
insoluble in Ether and Benzene
confirm
USP Reference standards USP Tetracaine Hydrochloride RS.
USP Endotoxin RS.
confirm
Melting point 145~150 degree 146.0~147.5 degree
Chromatographic purity In Pass confirm
Related substance Not more than the reference solution 0.05% confirm
Heavy metals ≤10ppm confirm
PH 4.5-6.5 5.8
Residue on ignition ≤0.10% 0.05%
Loss on Drying ≤ 0.5% 0.19%
Assay 98.0 -101.0% 100.1%
Conclusion Confirms USP 32



Application

(1) In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

(2) Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.

(3) Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

Local Anesthetic Agents Pain Killer Tetracaine / Tetracaine HCl CAS 136-47-0

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