Hangzhou Fuluo Biological Technology Co.,Ltd.
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|Packing:||Disguise||Appearance:||White Crystalline Powder|
99% Clomifene Citrate White crystalline raw pharma powder 50-41-9
EProduct Name: Clomiphene Citrate
Product Categories: API;Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Peptides;CLOMID
Mol File: 50-41-9.mol
Clomiphene Citrate Structure
Anti-hormone drugs Clomiphene citrate is a kind of anti-hormone drugs. It has strong anti-estrogenic effect and weak estrogenic effects, and is easily absorbed in the gastrointestinal tract, and can be slowly excreted through the liver into the bile duct; it is clinically useful in the treatment of women infertility with a certain level of estrogen but being anovulatory or less ovulatory and treatment of male infertility with luteal phase defect or few sperm;
it can also used for testing ovarian function and probing the dysfunction of male hypothalamus (pituitary) gonadal axis. The mechanism of action is to competitively bind to the hypothalamus estrogen receptor binding site for taking effect.
Estrogen is displaced out from these areas, then the hypothalamus will be aware of the apparent lack of circulating estrogen, leading to the release of gonadotropin hormone for stimulation of follicle stimulating hormone (FSH) and luteinizing hormone (LH) secretion with whom to trigge the normal menstrual cycle .
Chemical Properties It is white or white crystalline powder. Melting point 116.5-118 °C; it is slightly soluble in ethanol, chloroform, water, and insoluble in ether.
1. The product is an anti-estrogen (fertility inducer) drug used for treating dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecological diseases.
2. It is a kind of hormone drugs for treating luteal insufficiency, anovulatory infertility, dysfunctional uterine bleeding.
Chemical Properties Crystalline Solid
Usage An unducer of ovulation. A gonad-stimulating principle
Usage Synthetic estrogen agonist-antagonist. Gonad-stimulating principle.
Usage A selective estrogen receptor modulator
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