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|Molecular Weight:||232.28||Appearnace:||White Powder|
Raw materials Melatonine Pharmaceutical Melatonin,white powder 73-31-4
What's the Melatonin?
Melatonin is a hormone, secreted by the pineal gland in the brain that helps regulate other hormones and maintains the body's circadian rhythm. The circadian rhythm is an internal 24-hour time-keeping system that plays a critical role in determining when we fall asleep and when we wake up. Darkness stimulates the production of melatonin while light suppresses its activity.
Exposure to excessive light in the evening or too little light during the day can disrupt the body's normal melatonin cycles. For example, jet lag, shift work, and poor vision can disrupt melatonin cycles.
Melatonin can be used as medicine health care products, so as to enhance people's immune function, preventing aging and back to youth. What's more, it is also a kind of natural "sleeping pill".
Melatonin is a kind of hormone secreted by pineal body of pituitary gland in the body. The amount of melatonin has something to do with light. The weaker the light is, the more the melatonin is, whereas the less. In addition, it is helpful to one's sleep.
Melatonine as an anabolic hormone drugs, can promote protein synthesis and inhibiting protein dysplasia, and can lower blood cholesterol, reduce calcium phosphorus excretion and reduce bone marrow suppression, promoting development, promote tissue freshmen and granulation. Caused by long-term use of adrenal cortical hormone have prevention and protection against the adrenal cortex hypofunction.
The hormone melatonin plays a role in your natural sleep-wake cycle. Natural levels of melatonin in the blood are highest at night. Some research suggests that melatonin supplements taken at the right time might be helpful in treating jet lag or other sleep disorders that involve poor alignment of your natural biological clock with the night-day pattern around you. Melatonin might also reduce the time it takes to fall asleep - although this effect is typically mild.
Melatonin is a natural hormone made by your body's pineal (pih-knee-uhl) gland. This is a pea-sized gland located just above the middle of the brain. During the day the pineal is inactive. When the sun goes down and darkness occurs, the pineal is "turned on" by the SCN and begins to actively produce melatonin, which is released into the blood. Usually, this occurs around 9 pm. As a result, melatonin levels in the blood rise sharply and you begin to feel less alert. Sleep becomes more inviting. Melatonin levels in the blood stay elevated for about 12 hours - all through the night - before the light of a new day when they fall back to low daytime levels by about 9 am. Daytime levels of melatonin are barely detectable.
Melatonin might be more effective for other types of sleep issues, such as delayed sleep disorder or other sleep disorders affecting circadian rhythm.
A typical dose for treating insomnia is 0.3 milligrams (mg) to 5 mg of melatonin at bedtime. Different medical conditions, and people of different ages, will require different dosages of the medicine.
|Assay( HPLC )||99.0-102%||99.56%|
|Description||White or almost white, crystalline powder or colorless crystals.||White crystalline powder|
|Identification||IR & UV||Confirm|
|Melting point||116-120 °C||117.2-117.8 °C|
|Loss on drying||< 0.5%||0.18%|
|Residue on ignition||< 0.1%||0.07%|
|Related substances||< 0.1%||confirm|
|Heavy metal||< 10 ppm||0.8 ppm|
|total viable count||< 3000cfu/g||confirm|
|yeast and moulds||< 300cfg/g||confirm|