Description
LGD-4033 is a selective androgen receptor modulator (SARMS), and a novel non-steroidal oral SARM that binds to AR with high affinity (Ki of ~1 nM) and selectivity. It's in a class of androgen receptor (AR) ligands that is tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. LGD-4033 is expected to produce the therapeutic benefits of testosterone with improved safety, tolerability and patient acceptance due to tissue-selective mechanism of action and an oral route of administration.
Application
LGD can be used for bulking, recomposition and cutting. It possesses the ability to add size while still reducing body fat, akin to primobolan. Another excellent characteristic it possesses is that it can be ran up to 12 weeks, whereas most orals can only be used for 4-6 week time periods. LGD produces steady gains throughout the entire 12 weeks, and it provides a user with an overall sense of well being where you feel excellent throughout the entire time of use.
It has anabolic properties without the anabolic side effects. LGD-4033 also takes effect very quickly and will generally start to show results in the first week of use. In addition, it has shown to increase endurance, which will allow for more output during training, resulting in more gains being made. All these benefits make LGD ideal for any user because it provides an excellent kick-start and has an affinity to produce quality gains that show to be very clean but still substantial.
LGD-4033, a novel nonsteroidal, oral selective androgen receptor modulator, binds to the androgen receptor with high affinity and selectivity. It demonstrates anabolic activity in muscles, anti-resorptive and anabolic activity in bones and a robust selectivity for muscle and bone versus prostate and sebaceous glands. LGD-4033 has recently completed a Phase I Multiple Ascending Dose study in healthy volunteers. This randomized, double-blind, placebo-controlled Phase I study established the safety and tolerability up to doses of 22 mg per day.
Doses and Half-life
Anabolicum (LGD) is most commonly recommended at 5-10mg per day with once daily dosing schedule. The half-life of LGD is between 24-36hrs. It has been found to be well tolerated at up to 22mg/day in people.
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