CAS 6700-34-1 Dextromethorphan Hydrobromide
Product Name:Dextromethorphan Hydrobromide
CAS No.: 125-69-9
EINECS No.: 204-750-1
Appearance: White or kind of white crystalline powder
Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug. Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.
DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist.DXM and its major metabolite, dextrorphan, also acts as an NMDA receptor antagonist at high doses, which produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetics such as ketamine and phencyclidine. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.
DXM has dissociative effects, somewhat similar to ketamine and PCP. The main effects are those of dissociation (separation of mind and body), which include:
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