CAS 846589-98-8 Lorcaserin hydrochloride

Product Name: Lorcaserin HCl
CAS: 846589-98-8
MF: C11H14ClNClH
MW: 232.1525
Appearance:White Powder
Grade:Pharmaceutical Grade

Lorcaserin, currently marketed under the trade name Belviq and previously Lorqess during development,is a weight-loss drug developed by Arena Pharmaceuticals. It has serotonergic properties and acts as an anorectic.

Lorcaserin is used long term for weight loss in those who are obese.BELVIQ is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight adults with a weight-related medical problem, or obese adults, lose weight and keep it off.

Lorcaserin VS Orlistat

Lorcaserin is a selective 5-HT2C receptor agonist,and in vitro testing of the drug showed reasonable selectivity for 5-HT2C over other related targets. 5-HT2C receptors are located almost exclusively in the brain. The activation of 5-HT2C receptors in the hypothalamus is supposed to activate proopiomelanocortin (POMC) production and consequently promote weight loss through satiety.The safety and effectiveness was tested in the 3 clinical trials which nearly 8000 overweight or obese participants were involved.