99.7% Raw Local Anesthetic Powder Procaine With Fast Delivery
| Product Name: | PROCAINE |
| Synonyms: | 2-(Diethylamino)ethyl 4-aminobenzoate;2-(Diethylamino)ethyl p-aminobenzoate;2-(diethylamino)ethylp-aminobenzoate;2-diethylaminoethyl4-aminobenzoate;2-Diethylaminoethylester kyseliny p-aminobenzoove;2-diethylaminoethylesterkyselinyp-aminobenzoove;2-diethylaminoethylp-aminobenzoate;4-Aminobenzoic acid diethylaminoethyl ester |
| CAS: | 59-46-1 |
| MF: | C13H20N2O2 |
| MW: | 236.31 |
| EINECS: | 200-426-9 |
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| Mol File: | 59-46-1.mol |
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1, ester bond hydrolysis, temperature and pH affect the hydrolysis rate.
2, aromatic primary amine oxidation discoloration, preparation of injection should be adjusted to pH3.5-5.0, control the temperature and time of sterilization, to 100 degrees the flow of steam sterilization should be 30min, a pass into the inert gas, adding antioxidants, in addition to metal ions or adding metal ion masking agent, light, sealed, placed in the shade.
3, primary aromatic amino diazotization and coupling reaction can occur, which reacted with sodium nitrite in hydrochloric acid, alkaline solution generated 5 naphthol orange (scarlet) red precipitate diazotization compounds. Use..
Low toxicity is one of the commonly used local anesthetics. This drug is short acting anesthetic lipophilic esters, low, weak penetration of mucous membrane. It is not commonly used for topical anesthesia, often for local anesthesia, conduction anesthesia, subarachnoid anesthesia and epidural anesthesia.
After administration of 1-3min, the onset of 30-45min could be maintained, and the maintenance time could be prolonged by 20%. Procaine can be hydrolyzed in the plasma esterase, into aminobenzoic acid (PABA) and two ethylaminoethanol, the antibacterial effect against sulfonamides, it should avoid with sulfa drugs. Procaine can also be used for local closed injury. Excessive use can cause central nervous system and cardiovascular response. Sometimes can cause allergic reactions, it should be done before the skin allergy test, but negative skin test can still be allergic reactions. Instead of available chlorine procaine and lidocaine in the drug allergy.
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1, ester bond hydrolysis, temperature and pH affect the hydrolysis rate.
2, aromatic primary amine oxidation discoloration, preparation of injection should be adjusted to pH3.5-5.0, control the temperature and time of sterilization, to 100 degrees the flow of steam sterilization should be 30min, a pass into the inert gas, adding antioxidants, in addition to metal ions or adding metal ion masking agent, light, sealed, placed in the shade.
3, primary aromatic amino diazotization and coupling reaction can occur, which reacted with sodium nitrite in hydrochloric acid, alkaline solution generated 5 naphthol orange (scarlet) red precipitate diazotization compounds. Use.
