100.46% antidepressant drug Venlafaxine hydrochloride / Venlafaxine HCL
100G
MOQ
Negotiatable
Price
100.46% antidepressant drug Venlafaxine hydrochloride / Venlafaxine HCL
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Features
Basic Infomation
Place of Origin: Wuhan,Hubei
Brand Name: Yuancheng
Certification: ISO9001
Model Number: 99300-78-4
High Light:

raw materials testing pharmaceutical

,

raw material pharmaceutical

Payment & Shipping Terms
Packaging Details: Discreet packaging
Delivery Time: 4-7working days
Payment Terms: T/T, , MoneyGram,Bitcoin
Supply Ability: 5000KG/Month
Specifications
Name: Venlafaxine HCL
CAS: 99300-78-4
Molecular Formula: C17H28ClNO2
Formula Weight: 313.86
Apearance: White Crystalline Powder
Purity: 100.46%
Product Description

100.46% antidepressant drug Venlafaxine hydrochloride/Venlafaxine HCL

CAS No.:99300-78-4
Molecular Formula:C17H28ClNO2
Formula Weight: 313.86
Apearance:white crystalline powder
Purity:100.46%


Venlafaxine hydrochloride is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity

 

The COA:

 

Product name

 

venlafaxine hydrochloride

CAS No.

99300-78-4

 

Outer Packing

 

25kg/drum

 

Production date

July 2015

 

Shelf life

June 2020

 

Standard adopted

 

USP/IHT

 

Items of analysis

 

Specification

 

Results

 

 

description

 

 

off-white to white,crystalline 

 

 

white crystalline powder

 

 

solubility

 

 

soluble in methanol and in water

 

 

complies

 

A.IR absorption spectrum

 

sample spectrum should be concordant with that of the USP Venlafaxine hydrochlorider RS

 

 

sample spectrum was concordanted with reference standard spectrum

 

 

B.by HPLC

 

 

The retentiontime of the major peak of the sample solution corresponds to that of the standard solution,as obtained in the assay

 

complies

 

 

C.Test for chloride

 

 

to comply

 

 

complies

 

 

 

descyelohexanol venlafaxine

 

 

not more than 0.15%

 

 

0.028%

 

 

 

didesmethyl venlafaxine

 

not more than 0.15%

 

 

below detectable limit

 

 

 

venlafaxine related compound A

 

not more than 0.15%

 

 

below detectable limit

 

 

deoxy venlafaxine

 

 

not more than 0.15%

 

below detectable limit

 

 

any unknown individual impurity

 

 

not more than 0.1%

 

 

0.052%

 

 

total impurities

 

 

not more than 0.5%

 

 

0.12%

 

 

assay(by HPLC)

 

98.0%-102.0% calculated on the dried basis

 

 

100.46%

 

CLASS 1

 

 

solvents mentioned in (467) class 1 are not used in the process

 

 

 

 

 

CLASS 2

 

 

 

 

 

methanol

 

not more than 3000ppm

 

 

446 ppm

 

 

 

toluene

 

not more than 890 ppm

 

 

28 ppm

 

 

 

CLASS 3

 

 

 

 

 

acetone

 

 

not more than 5000ppm

 

 

iso propyl alcohol

not more than 5000ppm

 

1510ppm

 

 

Conclusion

 

Qualified

 

100.46% antidepressant drug Venlafaxine hydrochloride / Venlafaxine HCL 0

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