Pharmaceutical raw material Phenacetin hot in Canada CAS 62-44-2
Phenacetin (or acetophenetidin) is a pain-relieving and fever-reducing drug.
Phenacetin is a phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market.
Phenacetin is a synthetic, white crystalline solid that is slightly soluble in water and benzene, soluble in acetone and very soluble in pyrimidine.
PHYSICAL DESCRIPTION: Odorless fine white crystalline solid with a lightly bitter taste. Used as an analgesic medicine.
Product Name:Phenacetin
Alias:Phenacetinum,Acetophenetidin,4'-Ethoxyacetanilide;,4-Acetophenetidine,Para-Acetophenetidide
Assay:99%
CAS:62-44-2
EINECS:200-533-0
Molecular Formula:C10H13NO2
Molecular Weight:179.2158
Appearance:white flash scaly crystalline powder
Melting Point:134～137℃
Grade:Pharmaceutical Grade
Phenacetin is a pain-relieving and fever-reducing drug,it is metabolized as paracetamol (acetaminophen), which replaced it in some over-the-counter medications following the ban on phenacetin.
Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia.
Those who have taken drugs that contain phenacetin are more likely to develop cardiovascular disease, high blood pressure, anemia and cancer, and they are at a higher risk of death because of renal failure or diseases of the urinary system, according to various studies. A 1989 study showed that daily users of phenacetin were 5.1 times more likely to develop kidney disease than people who used the drug infrequently. The drug, which was also used in veterinary medicine, was shown to cause benign and malignant tumors in both mice and rats during experimental laboratory studies.
Some over-the-counter painkiller manufacturers replaced phenacetin with paracetamol, a similar drug that has not been shown to be a carcinogen. Paracetamol is also known as acetaminophen. Studies have shown that acetaminophen also can cause damage to the kidneys, but its side effects are not as serious as those of phenacetin.
Competitive Advantages of Phenacetin:
1. A Leading Manufacturer of Pharmaceutical Raw Material in mainland China. All items are factory
directly supplying, so we provide low price.
2. A great number of loyal customers all over the world.
3. Top quality products with the most favorable rate.
4. Free samples are available.
5. Flexible and untraceable payment terms
6. Exclusive customer service and 24/7 online helpful After-sale service.
COA of the Hot Product Phenacetin
| Product Name | Phenacetin | |
| Test Items | Specification | Test Results |
| Description | Should comply with the standard | Pass |
| Identification | Should be positive reaction | Pass |
| 4-chloroacetanilide | Should comply with standard | Pass |
| Sulphated ash | ≤0.1% | 0.06% |
| Melting point | 134℃ to 137℃ | 134℃ to 137℃ |
| Appearance | ≥99% | 99.3% |
| Conclusion | Complies with Enterprise Standard | |
Product Image of Hot Phenacetin
