White Crystalline Powder Male Sex Hormones Dutasteride For Hair Loss 164656-23-9
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White Crystalline Powder Male Sex Hormones Dutasteride For Hair Loss 164656-23-9
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Features
Basic Infomation
Place of Origin: China
Brand Name: YC
Certification: ISO9001
Model Number: CAS 164656-23-9
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natural male hormones

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male growth hormone

Payment & Shipping Terms
Packaging Details: As Requires
Delivery Time: Within 5-7 working days
Payment Terms: T/T, , MoneyGram,Bitcoin
Supply Ability: 5000kg/Month
Specifications
Product Name: Dutasteride
CAS: 164656-23-9
MF: C27H30F6N2O2
MW: 528.5297
Appearance: White Crystalline Powder
Grade: Pharmaceutical Grade
Product Description

 

               Sex enhancemant pharmaceutical raw material Dutasteride for hair loss

 

Product name:Dutasteride
Alias:Duagen; Dutas
CAS:164656-23-9
MF:C27H30F6N2O2
MW:528.5297
Appearance: White crystalline powder
Grade: Pharmaceutical Grade

Melting point:242-250°C


Description

 

A synthetic 4-azasteroid compound that is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5 alpha-reductase, an intracellular enzyme that converts testosterone to DHT.

 

Dutasteride is chemically designated as (5α,17β)-N-{2,5 bis(trifluoromethyl)phenyl}-3-oxo-4- azaandrost-1-ene-17-carboxamide. The empirical formula of dutasteride is C27H30F6N2O2, representing a molecular weight of 528.5

 

Dutasteride is a white to pale yellow powder with a melting point of 242° to 250°C. It is soluble in ethanol (44 mg/mL), methanol (64 mg/mL), and polyethylene glycol 400 (3 mg/mL), but it is insoluble in water.


Dutasteride is used for:

 

Treating symptoms of benign prostatic hyperplasia (BPH) or enlargement of the prostate gland. It also helps to reduce the risk of urinary blockage and the need for surgery to treat BPH. It may be used alone or along with another medicine (tamsulosin).

 

Dutasteride is a 5 alpha-reductase enzyme inhibitor. It works by lowering levels of a hormone called dihydrotestosterone (DHT), which is a major cause of prostate growth. Lowering DHT leads to shrinkage of the enlarged prostate gland.

 

Dutasteride is a medication used to treat benign prostatic hyperplasia (enlarged prostate) and androgenetic alopecia (pattern hair loss).


Medical uses

 

Avodart (dutasteride) 500 µg soft capsules
Prostate enlargement
Dutasteride is occasionally used for treating benign prostatic hyperplasia (BPH); colloquially known as an "enlarged prostate". It is approved by the Food and Drug Administration (FDA) in the U.S. for this indication.

Prostate cancer

Pattern hair loss

Dutasteride is approved for the treatment of male androgenetic alopecia in South Korea at a dosage of 0.5 mg per day. It has been found in several studies to improve hair growth in men more rapidly and to a greater extent than 2.5 mg/day finasteride. Dutasteride has also been used off-label in the treatment of female pattern hair loss.

 

Excessive hair growth

 

Although no reports specific to dutasteride currently exist, 5α-reductase inhibitors like finasteride have been found to be effective in the treatment of hirsutism (excessive facial and/or body hair growth) in women. Dutasteride may be more effective than finasteride for this indication due to the fact that its inhibition of the 5α-reductase enzyme is comparatively more complete.


Is There Any Difference in Side Effects Between Dutasteride and Finasteride?

 

GlaxoSmithKline protocol ARI40001 compared dutasteride (0.5 mg/d) with finasteride (5 mg/d) for 1 year.18 There were no significant differences in the incidence of the most common drug-related adverse events between the dutasteride and finasteride groups. The only adverse events that the investigators considered to be drug-related that occurred at an incidence of more than 2% were impotence and decreased libido.

 

COA

 

Test Items Specification Test Results
Description White or almost white crystalline powder Complies
Identification Meet the requirements Complies
Loss on drying ≤0.5% 0.2%
Melting range 246oC~252oC 246oC~248oC
Heavy metals ≤20ppm Complies
Residue on ignition ≤0.1% Complies
Related substances Biggest Impurities≤0.5% 0.36%
  Total Impurity≤1.0% 0.7%
Assay 97.0%~103.0% 99.3%
Conclusion Complies with In-house Standard

 

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